What question did this study set out to answer?

To illustrate an unusual presentation of breast carcinoma through bone fractures leading to delayed diagnosis.

January 23, 2026MRIMS Journal of Health Sciences0 citationsOpen Access

Beyond the break: Breast carcinoma unveiled – An unusual case report

NBNadira Begum NSNoor Mariam ShaikDeccan College of Medical Sciences NTNaushaba TazeenDeccan College of Medical Sciences

Key Points

To illustrate an unusual presentation of breast carcinoma through bone fractures leading to delayed diagnosis.
Case report detailing clinical presentation and pathological findings.
Imaging studies performed to identify primary tumors and skeletal involvement.
Pathological assessment conducted on bone tissue samples.
Individual presented with left femur and right humerus fractures after minor fall.
Pathological examination confirmed metastatic carcinoma in bone tissue.
Imaging studies revealed a primary breast lesion with widespread skeletal metastases.

Abstract

Abstract Unusual initial presentations of common malignancies can lead to delayed diagnosis and treatment. We report the case of a 49-year-old woman who presented with fractures of the left femur and right humerus following a minor fall. Unexpectedly, pathological examination of the bone tissue revealed metastatic carcinoma. Imaging studies subsequently identified a primary lesion in the right breast with widespread skeletal involvement . Only 0.4%–1% of breast cancer patients initially present with symptoms of bone metastasis . This case emphasises the crucial role of vigilance and pathological assessment in uncovering hidden primary malignancies. It also highlights the need to consider underlying carcinoma as a differential diagnosis even in routine orthopaedic cases of low-impact fractures.

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