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January 23, 2026Journal of Crohn s and Colitis

P0560Sarcopenia and Clinical Outcomes in Inflammatory Bowel Disease: A Prospective Monocentric Study

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Authors

HAHala AouroudMAM AouroudONO. Nacir

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Overview

Prospective study examines sarcopenia's role in adverse outcomes in IBD, suggesting the need for routine screening.

Key Points

  • This study aims to assess the prevalence of sarcopenia in patients with inflammatory bowel disease and its impact on clinical outcomes over six months.
  • Conducted a prospective monocentric study at a university hospital.
  • Included 98 patients with Crohn’s disease and ulcerative colitis.
  • Sarcopenia assessed using EWGSOP2 criteria and various nutritional and inflammatory measures.
  • Primary endpoint was a composite event at six months including relapse and hospitalization.
  • Statistical analyses included univariate comparisons and multivariate Cox regression.
  • 34.7% of patients were found to have sarcopenia.
  • Sarcopenic patients had significantly lower BMI and albumin levels compared to non-sarcopenic patients.
  • 41.8% of all patients experienced adverse outcomes, with higher rates among sarcopenic subjects.
  • Sarcopenia was identified as an independent predictor of adverse outcomes in multivariate analysis.

Cite This Study

Aouroud et al. (2026) studied this question.

synapsesocial.com/papers/69730ef2c8125b09b0d1ebbbhttps://doi.org/10.1093/ecco-jcc/jjaf231.741
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1P1066Ultra-processed food intake independently predicts pre-sarcopenia in patients with inflammatory bowel disease in remission2026
  2. 2Increased mortality associated with sarcopenia in inflammatory bowel disease: a long-term prospective cohort study2025 · 1 citations
  3. 3Sarcopenia in Inflammatory Bowel Disease: Prevalence, Mechanisms, Detection, Adverse Clinical Impact and Targetable Care Gaps—A Narrative Review Supported by a Structured Literature Search2026
  4. 4P0355Prevalence of malnutrition and sarcopenia in hospitalized patients with inflammatory bowel diseases: a multimodal cross-sectional study2026
  5. 5P0222Determinants of Sarcopenia in Crohn’s Disease: Effects of Short Bowel Syndrome and Protein Intake2026