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August 20, 2025The American Journal of Gastroenterology

Increased mortality associated with sarcopenia in inflammatory bowel disease: a long-term prospective cohort study

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Authors

QZQian ZhangTongji UniversityHLHaoxi LiuMinistry of Education and Child CareSLSi LiuNortheast Agricultural University

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Implication

Prospective cohort study shows increased mortality risk in older adults with sarcopenia, suggesting a need for assessment in IBD patients.

Key Points

  • Probable and confirmed sarcopenia significantly increase long-term mortality risk in IBD patients, impacting health outcomes.
  • Among patients with probable sarcopenia, mortality risk increases by 47%, while those with confirmed sarcopenia face a 140% higher risk.
  • This study involved a prospective cohort of 4,966 patients, with a median follow-up period of 14.6 years to assess outcomes.
  • Sarcopenia assessment is valuable for risk stratification, particularly in older individuals with inflammatory bowel disease.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68af4cd8ad7bf08b1ead627chttps://doi.org/10.14309/ajg.0000000000003734
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