Key result
Functional extra-stimulus mapping with EGM DeEP maps achieves highest accuracy in identifying arrhythmogenic substrates.
Why the study?
Does functional ES mapping using EGM duration prolongation DeEP maps improve accuracy in defining the arrhythmogenic substrate for ventricular tachycardia?
Does functional ES mapping using EGM duration prolongation DeEP maps improve accuracy in defining the arrhythmogenic substrate for ventricular tachycardia?
EGM duration prolongation DeEP maps provide the highest accuracy for defining arrhythmogenic substrate during VT functional extra-stimulus mapping, without added benefit from latency or NF EGM annotation.
Answers are grounded in this paper and cite their sources.
Supports preclinical DeEP mapping for VT substrates; leaves open human translation and clinical validation.
Functional ES mapping using EGM duration prolongation DeEP maps yielded the highest accuracy in defining the arrhythmogenic substrate. The inclusion of latency or annotation of NF EGM components does not improve functional substrate mapping accuracy.
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Mayer et al. (2025) studied this question. Functional extra-stimulus mapping using EGM duration prolongation DeEP maps achieved the highest accuracy in identifying arrhythmogenic substrates.
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