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Research Paper | Synapse

January 25, 2026Critical Care0 citationsOpen Access

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Fluid responsiveness and changes in venous congestion and lung water during volume expansion in critically ill patients: a multicentre observational study

XSXiang SiInserm DCDaiyin CaoInserm RSRui ShiSun Yat-sen University

Key Points

This study aims to understand the effects of volume expansion on venous congestion and fluid responsiveness in critically ill patients.
Conducted a multicentre observational study
Monitored venous congestion using VExUS and CVP assessments
Categorized patients into fluid responders and non-responders
Fluid challenge worsened venous congestion in non-responders
No worsening of venous congestion observed in fluid responders

Abstract

A fluid challenge worsened venous congestion, assessed by VExUS as well as CVP, in fluid non-responders, while it was not in fluid responders.

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Cite This Study

Si et al. (Thu,) studied this question.

synapsesocial.com/papers/6975b229feba4585c2d6daa4 https://doi.org/https://doi.org/10.1186/s13054-025-05803-y