Fluid responsiveness and changes in venous congestion and lung water during volume expansion in critically ill patients: a multicentre observational study

Key Points

This study aims to understand the effects of volume expansion on venous congestion and fluid responsiveness in critically ill patients.
Conducted a multicentre observational study
Monitored venous congestion using VExUS and CVP assessments
Categorized patients into fluid responders and non-responders
Fluid challenge worsened venous congestion in non-responders
No worsening of venous congestion observed in fluid responders

Observational study reveals fluid challenge worsens venous congestion in non-responders, suggesting important clinical implications.

A fluid challenge worsened venous congestion, assessed by VExUS as well as CVP, in fluid non-responders, while it was not in fluid responders.

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Si et al. (2026) studied this question.

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