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January 25, 2026BMC Infectious DiseasesOpen Access

Clinical and microbiological characteristics of polymicrobial bloodstream infections in hematologic malignancy patients: a cross-sectional study

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Authors

NDNur OGUZ DAVUTOGLUMuğla UniversityCYCihan YEŞİLRize Devlet HastanesiBÇBurak Ekrem ÇitilMuğla University

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Implication

This cross-sectional study identifies risk factors for mortality in patients with bloodstream infections, suggesting strategies for improvement.

Key Points

  • This research aims to identify risk factors associated with poor outcomes from polymicrobial bloodstream infections in patients with hematological malignancies.
  • Conducted a retrospective review of medical records from 2017 to 2024.
  • Analyzed demographics, laboratory results, microbiological isolates, and antibiotic susceptibility.
  • Defined PBSIs as infection with two or more bacterial species isolated from blood cultures.
  • Out of 108 patients, 21 (19.4%) had PBSIs.
  • Common pathogens included coagulase-negative staphylococci, Klebsiella spp., and Pseudomonas aeruginosa.
  • 58.3% of infections involved multidrug-resistant organisms.
  • The mortality rate for PBSI patients was 57.1%.
  • Risk factors for mortality included ICU admission, mechanical ventilation, and renal failure.

Cite This Study

DAVUTOGLU et al. (2026) studied this question.

synapsesocial.com/papers/6975b306feba4585c2d6e7d0https://doi.org/10.1186/s12879-026-12660-9
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