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January 25, 2026Current Molecular Medicine

Phosphatidylethanolamine: Structural Component and Beyond

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Authors

SPSwaroop Kumar PandeyAKAyush KulshreshthaAMAnuja Mishra

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Overview

This review explores physiological roles of phosphatidylethanolamine in disease, indicating its potential as a lipid biomarker.

Key Points

  • The aim is to summarize the physiological roles of phosphatidylethanolamine and its implications in human health and disease.
  • Review of lipid metabolism pathways including CDP-ethanolamine and PSD pathways.
  • Analysis of the role of phosphatidylethanolamine in cell signaling and membrane dynamics.
  • Examination of lipidomics to identify disease-specific lipid biomarkers.
  • Phosphatidylethanolamine is crucial for membrane fluidity and protein function.
  • Altered levels of phosphatidylethanolamine are linked to metabolic and neurodegenerative diseases.
  • Comprehensive profiling of phosphatidylethanolamine aids in identifying potential lipid biomarkers for various diseases.

Cite This Study

Pandey et al. (2026) studied this question.

synapsesocial.com/papers/6975b36bfeba4585c2d6eec4https://doi.org/10.2174/0115665240415642251205104453
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lysophosphatidylethanolamine (LysoPE) in health and disease: a narrative review of its pathophysiological mechanisms and translational potential as a biomarker2026
  2. 2BPS2026 – Biophysical characterization of phosphatidylethanolamine bilayers2026
  3. 3Metabolic Labeling of Phosphatidylethanolamine Lipids in Cells Using Clickable Ethanolamine Analogs2026
  4. 4BEYOND LITTLE HANDSHAKE: ROLE OF PHOSPHOLIPIDS IN HEALTH AND DISEASE2026
  5. 5Photoaffinity Labeling Reveals a Role for the Unusual Triply Acylated Phospholipid <i>N</i>-Acylphosphatidylethanolamine in Lactate Homeostasis2025