Tissue-based map of the human proteome
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Overview
Proteomic mapping reveals protein and RNA expression patterns across 32 human tissues, highlighting tissue-specific protein distribution and function.
Key Points
- To comprehensively map the dynamic expression and spatial localization of proteins encoded by approximately 20,000 human genes across major tissues.
- Measured gene expression at the RNA level across 32 human tissues.
- Conducted antibody profiling to spatially localize corresponding proteins within tissue samples.
- Generated a comprehensive spatial map of protein and transcript expression across 32 diverse human tissues.
- Provided an interactive online database enabling detailed exploration of systemic protein distribution patterns throughout the human body.
Cite This Study
Uhlén et al. (2015) studied this question.