The study synthesizes and tests antimicrobial agents against bacteria and fungi, suggesting potential applications in medicine.
2-Amino-4-(2’-n-butyl-4’-chloro-1’-H-imidazol-5’-yl)-6-aryl nicotinonitriles. (2a-2j); 2-Methoxy-4-(2’-n-butyl-4’-chloro-1’-H-imidazol-5’-yl)-6-aryl nicotinonitriles. (3a-3j) have been synthesized. The products have been assayed for their antimicrobial activity against Gram +ve bacteria and Gram –ve bacteria and fungi. The products have been characterized by IR, 1HNMR, Mass Spectra and TLC.
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Joshi et al. (2022) studied this question.
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