Investigates the antimicrobial activity of synthesized pyrazoles in Gram-positive and Gram-negative bacteria, indicating potential therapeutic applications.
5-(2’-n-butyl-4’-chloro 1’-H-imidazol- 5’-yl)-3-aryl-4, 5-dihydro-1-H-pyrazoles. (2a-2j); 1-[5’-(2”-n-butyl-4”- chloro-1”-H-imidazol-5”-yl)-3’-Aryl-4’, 5’-dihydro-1’-H-pyrazol-1-yl]-ethanones. (3a-3j); 5-(2’-n-butyl-4’-chloro-1’-H-imidazol-5’-yl)-3-Aryl-1-phenyl-4, 5-dihydro-1-H-pyrazoles. (4a-4j) have been synthesized. The products have been assayed for their antimicrobial activity against Gram +ve bacteria and Gram –ve bacteria and antifungal activity. The products have been characterised by IR, 1HNMR, Mass Spectra and TLC.
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Joshi et al. (2021) studied this question.
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