What question did this study set out to answer?

To evaluate the mosquito larvicidal, pupicidal, and antimicrobial properties of methanol extract fractions from Phyla nodiflora leaves.

January 27, 2026Open Access

Entomotoxicity properties of eco-friendly methanol extract fractions from Phyla nodiflora (L.) Greene leaf exhibits mosquito larvicidal, pupicidal and antimicrobial activity

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Demonstrates mosquito larvicidal and antimicrobial activity of Phyla nodiflora leaf extract fractions, suggesting potential for vector control.

To evaluate the mosquito larvicidal, pupicidal, and antimicrobial properties of methanol extract fractions from Phyla nodiflora leaves.
Characterization of methanol leaf extract fractions (Pn-MLEFr) using TLC, CC, FTIR, and GC-MS.
Assessment of larvicidal and pupicidal activity on Anopheles stephensi larvae at concentrations of 1, 3, and 5 ppm.
Identification of 21 compounds in extract fractions through GC-MS analysis.
Pn-MLE Fr-6 exhibited the highest LC50 and LC90 values of 25.80 and 68.45 ppm.
At 1 ppm, it achieved a mortality percentage (TM%) of 78% and no adults emerged at 5 ppm.
Ergosta-5,22-dien-3-ol, acetate was identified as a major compound contributing to the activity.

Irrusappan et al. (2022) studied this question.

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Demonstrates mosquito larvicidal and antimicrobial activity of Phyla nodiflora leaf extract fractions, suggesting potential for vector control.