Key result
Blood pressure lowering reduces death and CVD risk when baseline SBP is 140 or higher.
Why the study?
Does blood pressure lowering reduce death and CVD across different baseline blood pressure levels in primary prevention and CHD patients?
Population
Patients evaluated for primary prevention of cardiovascular disease and patients with coronary heart disease
Authors
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Supports BP lowering at SBP ≥140 mm Hg in primary prevention; confirms and extends prior trial evidence across large populations.
Does blood pressure lowering reduce death and CVD across different baseline blood pressure levels in primary prevention and CHD patients?
Blood pressure lowering for primary prevention is beneficial when baseline SBP is ≥140 mm Hg, while patients with established CHD may benefit from treatment at lower BP levels.
Brunström et al. (2017) studied this question. Blood pressure lowering is associated with reduced risk of death and cardiovascular disease in patients with baseline SBP of 140 mm Hg or higher.
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