Key result
Higher homocysteine levels are associated with increased aortic stiffness in elderly individuals, particularly among the oldest old.
Why the study?
Is homocysteine level associated with aortic stiffness in older persons?
Is homocysteine level associated with aortic stiffness in older persons?
The strong association between homocysteine and cardiovascular mortality in the elderly may be mediated by aortic stiffness.
Supports possible mediation of homocysteine-CV mortality link by aortic stiffness in elderly; leaves open causality and intervention effects.
In older persons, homocysteine is associated with aortic stiffness, predominantly in the oldest old. This suggests that the strong association between homocysteine and cardiovascular mortality in the elderly may be mediated by aortic stiffness.
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Dijk et al. (2013) studied this question. Higher homocysteine levels are associated with increased aortic stiffness in elderly individuals, particularly among the oldest old.
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