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February 2, 2026Journal of Nutritional ScienceOpen Access

Inclusion of stabilised rice bran in ready-to-use therapeutic food supports growth in Indonesian children with severe and moderate acute malnutrition: solutions to enhance health with alternative treatments (SEHAT), a double-blinded, randomised clinical trial

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Authors

SBSilvia BarbazzaDepartment of HealthAWAnnika WeberMax Planck Institute of PsychiatryMFMoretta D FauziCentre de Coopération Internationale en Recherche Agronomique pour le Développement

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Overview

Double-blinded trial shows that rice bran in therapeutic food improves growth in children with acute malnutrition, suggesting better treatment options.

Key Points

  • The study aims to evaluate the effectiveness of including rice bran in ready-to-use therapeutic foods for treating acute malnutrition in children.
  • Conducted a double-blinded, randomised controlled trial.
  • Enrolled 200 children aged 6–59 months with severe acute malnutrition.
  • Compared two RUTF formulations: one with rice bran and one without.
  • Measured primary outcomes: weight, mid-upper arm circumference (MUAC), and anthropometric z-scores.
  • Applied linear mixed models for analysis across different age groups.
  • At week 4, RUTF with rice bran showed significantly greater weight gain velocity (p = 0.02) compared to RUTF without rice bran.
  • MUAC velocity was also significantly higher with the RUTF+rice bran treatment (p = 0.004).
  • No significant differences were found in other anthropometric outcomes across treatment groups at subsequent time points.

Cite This Study

Barbazza et al. (2026) studied this question.

synapsesocial.com/papers/6980fbbec1c9540dea80d8efhttps://doi.org/10.1017/jns.2025.10074
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Gut Microbiota-Targeted Treatment of Severe Acute Malnutrition Using Rice Bran in Ready-to-Use Therapeutic Foods: A Randomized Controlled Trial in Indonesia2024 · 1 citations
  2. 2Addition of Prebiotic Rice Bran to Ready-to-Use Therapeutic Food Modulated Changes in Body Composition Only of 6–23-Month-Old Children During Treatment for Uncomplicated Acute Malnutrition: The Solutions to Enhance Health with Alternative Treatment (SEHAT) Study2026
  3. 3Rice Bran Supplements the Nutritional Density of Ready‐to‐Use Therapeutic Foods: A Targeted Nutrient and Non‐Targeted Metabolomic Analysis2026 · 2 citations
  4. 4The efficacy of ‘ready-to-use therapeutic food - RUTF’ without milk to modulate severe acute malnutrition (SAM) in low- and middle-income countries (LMICs): a scoping review2025 · 2 citations
  5. 5Effectiveness of Home-Based Administration of Ready to Use Therapeutic Formula (RUTF) in the Management of Severe Acute Malnutrition (SAM)2024 · 1 citations