A case report demonstrates cerebral venous sinus thrombosis complicating spontaneous intracranial hypotension, suggesting clinicians monitor for this association.
Spontaneous intracranial hypotension (SIH) is caused by leakage of cerebrospinal fluid (CSF) within the spinal column, and it is a rare risk factor for cerebral venous sinus thrombosis (CVST), which is a life-threatening condition. We present a case of SIH with further developed CVST causing intracranial hypertension. Discussions were made on the mechanisms of SIH, leading to CVST and the presentations and treatment of SIH. Clinicians should keep in mind the coexistence of CVST and SIH. Patients with CVST should be closely observed for any change in the headache pattern such as orthostatic headache, which might suggest the coexistence of SIH. This directs treatment toward the identification and management of occult CSF leaks.
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Hsu et al. (2026) studied this question.
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