What question did this study set out to answer?

This research aims to assess the prevalence and characteristics of laryngopharyngeal reflux in patients with laryngeal contact granuloma using objective monitoring methods.

February 2, 2026The Laryngoscope

Objective Assessment of Laryngopharyngeal Reflux in Laryngeal Contact Granuloma

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This research aims to assess the prevalence and characteristics of laryngopharyngeal reflux in patients with laryngeal contact granuloma using objective monitoring methods.
Conducted a retrospective analysis of patients diagnosed with laryngeal contact granuloma
Utilized 24-hour hypopharyngeal–esophageal multichannel intraluminal impedance–pH monitoring
Classified reflux episodes by acidity and posture
Compared clinical characteristics and reflux episode profiles between reflux-positive and reflux-negative groups
61% of patients were identified as reflux-positive, while 39% were reflux-negative
Most reflux episodes were weakly acidic (46.2%) and weakly alkaline (44.3%), with acidic events being rare (9.5%)
94.8% of reflux events occurred in upright posture
A greater proportion of reflux-positive unilateral lesions were found on the left side (76.2%) versus the right (23.8%)
Symptom screening had low sensitivity (50%) and specificity (46.7%) for determining reflux status

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Implication

Retrospective study finds strong links between reflux status and laryngeal contact granuloma characteristics, suggesting better diagnostic methods.

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/6980fe57c1c9540dea810532 https://doi.org/10.1002/lary.70407

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Implication

Retrospective study finds strong links between reflux status and laryngeal contact granuloma characteristics, suggesting better diagnostic methods.

Objective Assessment of Laryngopharyngeal Reflux in Laryngeal Contact Granuloma

Key Points

Discussion

Implication

Cite This Study

Objective Assessment of Laryngopharyngeal Reflux in Laryngeal Contact Granuloma

Key Points

Discussion

Implication

Cite This Study

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