What question did this study set out to answer?

To determine the prevalence and potential causative role of laryngopharyngeal reflux in adult patients presenting with idiopathic or secondary subglottic stenosis.

July 1, 2001Annals of Otology Rhinology & Laryngology

Association of Laryngopharyngeal Reflux Disease and Subglottic Stenosis

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Authors

NMNicole MaronianUniversity Hospitals of Cleveland PWPatricia F. WaughDurham University HAHafez AzadehSeattle University

Discussion

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Implication

Retrospective chart review reveals laryngeal acid exposure in 86% of patients with subglottic stenosis, suggesting reflux contributes significantly to airway narrowing.

Key Points

To determine the prevalence and potential causative role of laryngopharyngeal reflux in adult patients presenting with idiopathic or secondary subglottic stenosis.
Conducted a retrospective chart review of 19 adult patients diagnosed with subglottic stenosis between 1991 and 1999 (10 with secondary underlying conditions and 9 idiopathic cases).
Assessed 14 patients using 24-hour ambulatory pH monitoring with 3- or 4-port catheters positioned at the laryngeal inlet under manometric guidance.
Laryngeal acid exposure (pH < 4) occurred in 12 of 14 tested patients (86%), with reflux persisting in half of patients despite empirical proton pump inhibitor therapy.
Hypopharyngeal acid exposure was detected in 100% (7 of 7) of tested patients with underlying systemic conditions and in 71% (5 of 7) of tested patients with idiopathic subglottic stenosis.

Cite This Study

Maronian et al. (2001) studied this question.

synapsesocial.com/papers/6a83be4620cfb2932ffe1e51 https://doi.org/10.1177/000348940111000703

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Implication

Retrospective chart review reveals laryngeal acid exposure in 86% of patients with subglottic stenosis, suggesting reflux contributes significantly to airway narrowing.

Association of Laryngopharyngeal Reflux Disease and Subglottic Stenosis

Discussion

Member takes

Implication

Key Points

Cite This Study

Association of Laryngopharyngeal Reflux Disease and Subglottic Stenosis

Discussion

Member takes

Implication

Key Points

Cite This Study

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