Key result
OSA progression is linked to increased atrial epicardial fat volume independent of visceral fat.
Why the study?
Does severe obstructive sleep apnea independently associate with increased epicardial adipose tissue volume and altered attenuation in patients without cardiovascular disease or diabetes compared to mild-moderate obstructive sleep apnea?
Observational (n=180)
No
Does severe obstructive sleep apnea independently associate with increased epicardial adipose tissue volume and altered attenuation in patients without cardiovascular disease or diabetes compared to mild-moderate obstructive sleep apnea?
Reveals the link between obstructive sleep apnea and epicardial adipose tissue distribution in patients, suggesting implications for cardiovascular risk assessment.
OSA progression without cardiovascular disease and diabetes may promote an increase in EATV, especially in the atrial region. In addition, the change in epicardial adipose tissue appears to be independent of visceral adipose tissue. This underscores EAT as a distinct fat depot and highlights its potential role in early cardiovascular risk assessment for OSA patients, offering perspectives for future research into mechanistic pathways and clinical interventions.
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Wang et al. (2026) conducted an observational in Obstructive sleep apnea (n=180). Severe obstructive sleep apnea vs. Mild-moderate obstructive sleep apnea was evaluated on Epicardial adipose tissue volume (EATV) (MD 12.05, 95% CI 1.99 to 22.11, p=0.020). Severe obstructive sleep apnea was independently associated with increased epicardial adipose tissue volume (MD 12.05) compared to mild-moderate disease, even after controlling for visceral adiposity.
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