What question did this study set out to answer?

This research aims to evaluate bone and body composition in girls with precocious puberty, premature thelarche, and healthy prepubertal controls.

Bone and Body Composition by DXA in Girls with Precocious Puberty, Premature Thelarche, and Prepubertal Controls

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Observational study assesses bone and body composition in girls with early puberty and controls, indicating significant differences.

This research aims to evaluate bone and body composition in girls with precocious puberty, premature thelarche, and healthy prepubertal controls.
Analyzed 184 girls aged 5-9 years with suspected precocious puberty or early puberty, and 47 prepubertal controls.
Conducted dual-energy X-ray absorptiometry (DXA) to measure bone and body composition, including lumbar spine BMD and fat mass.
Compared various bone and body composition measures across different groups.
Girls with precocious puberty/early puberty showed significantly higher height, BMI SDS, and bone age compared to controls.
Greater lumbar spine BMD and fat-free mass index were also observed in the CPP/EP group.
The premature thelarche group exhibited higher central adiposity but similar bone density measures to the precocious puberty group.

Fava et al. (2026) studied this question.

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