Key result
Pregnancy-related acute myocardial infarction occurs at a rate of 6.2 per 100,000 deliveries, with age 40+ having a 30-fold higher risk than those <20 years.
Why the study?
What are the incidence, mortality, and risk factors for acute myocardial infarction in pregnant and postpartum women?
Population
Pregnant and postpartum women in the United States (pregnancy-related hospital discharges)
Design
Cohort
Follow-up
In-hospital (discharge data)
Authors
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Alerts clinicians to sharp age-related MI risk in pregnancy; leaves open prospective validation of modifiable factors.
What are the incidence, mortality, and risk factors for acute myocardial infarction in pregnant and postpartum women?
Pregnancy increases the risk of acute myocardial infarction 3- to 4-fold, with hypertension, thrombophilia, diabetes, and smoking acting as significant, potentially modifiable risk factors.
James et al. (2006) studied this question. Pregnancy-related acute myocardial infarction occurs at a rate of 6.2 per 100,000 deliveries, with age 40+ having a 30-fold higher risk than those <20 years.
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