Intralesional 5 fluorouracil in the management of hypertrophic oculofacial scar

A 40-year-female came with chief complaints of scar on the lateral side of the right eye which was extending from lateral canthus to the inferior orbital rim associated with pain and redness over scar. She had history of road traffic accident 1 month back. Her anterior and posterior segment examination was normal with 20/20 visual acuity in both eyes. There was no history of systemic disease. On the first visit, the patient was advised massage over scar with antibiotic steroid ointment to reduce pain and inflammation. In the next follow-up, 0.4–0.6 ml of 5 fluorouracil (5 FU) (50 mg/ml) injection was given subcutaneously at scar. The patient was advised scar massage with antibiotics steroid ointment and ointment containing alium cepa extract, heparin sodium, and allantoin gel for 6 months after 5 FU injection. On post-treatment follow-up, reduction in scar volume and erythema was noted and subjectively, and tightness of skin and pain reduced without side effects.