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February 5, 2026Drug Development Research

Halting Tuberculosis in Its Tracks: Advances and Strategies for Discovering Therapeutic Targets in Mycobacterium tuberculosis

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Authors

ASAyushi SharmaCentral University of PunjabGSGyanendra SinghNational Institute of Occupational HealthRSRahul ShrivastavaVivekananda Global University

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Implication

This review highlights new therapeutic targets and strategies for overcoming drug-resistant tuberculosis, indicating future therapeutic possibilities.

Key Points

  • The aim is to explore novel drug targets and strategies for effective tuberculosis treatment and control.
  • Review of current drug targets associated with Mycobacterium tuberculosis
  • Analysis of approved drugs like delamanid and bedaquiline
  • Discussion of ongoing preclinical and clinical drug developments
  • Identification of key drug targets such as ATP synthase and isocitrate lyase
  • Highlighting the significance of novel drug leads for MDR and XDR tuberculosis
  • Emphasis on strategies that enhance drug discovery for tuberculosis treatment

Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/6984348bf1d9ada3c1fb2ce5https://doi.org/10.1002/ddr.70239
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