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This open-label study demonstrates skin quality and volume improvements with a hyaluronic acid-polynucleotide filler, indicating effective facial rejuvenation.
The HA-PN hybrid filler demonstrated improvements in midface volume restoration with concurrent improvements in skin barrier function, hydration, and elasticity, and was well tolerated over 24 weeks within the constraints of the study design.
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Lee et al. (2026) studied this question.
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