What question did this study set out to answer?

This research aims to evaluate the antimalarial effectiveness of Mangifera indica extracts against Plasmodium falciparum.

February 5, 2026Open Access

In vitro antimalarial activity of the extracts of Mangifera indica L. against Plasmodium falciparum gotten from children under fifteen years attending Federal Medical Center Jalingo, Taraba State, Nigeria

View Full Paper

Ask AI

Bookmark

This research aims to evaluate the antimalarial effectiveness of Mangifera indica extracts against Plasmodium falciparum.
Conducted in vitro tests using aqueous and ethanolic extracts of M. indica leaves and stem bark.
Performed qualitative phytochemical screening to identify secondary metabolites.
Measured mean parasitized cell counts and percentage inhibition across various extract concentrations.
Calculated IC₅₀ values to quantify the effectiveness of the extracts.
Aqueous extracts showed high saponin content, while ethanolic extracts contained elevated alkaloid levels.
All extracts significantly reduced parasitized cell counts in a concentration-dependent manner.
Ethanolic stem bark and leaf extracts achieved the lowest parasitemia levels at 3.13 μg/mL.
High percentage inhibition was noted in ethanolic extracts, indicating strong antiplasmodial activity.
Combination extracts demonstrated consistent synergistic effects in inhibiting P. falciparum.

No takes yet. Share an insight, caveat, or question.

Examines the antimalarial effects of Mangifera indica extracts in children, suggesting potential natural treatments.

Kolawole et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark