Key result
Higher NT-proBNP is linked to increased dementia and cognitive decline risk over 10 years.
Why the study?
Is NT-proBNP associated with the risk of dementia and cognitive decline in the general population?
Is NT-proBNP associated with the risk of dementia and cognitive decline in the general population?
NT-proBNP may serve as a useful biomarker for predicting imminent cognitive decline and dementia in individuals without clinical cardiovascular disease.
May support cognitive risk stratification in primary care; extends observational links but leaves causality and practice change open.
NT-proBNP reflecting subclinical CVD is associated with dementia, particularly vascular dementia. NT-proBNP can be a useful marker of imminent cognitive-decline and dementia in absence of clinical CVD.
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Mirza et al. (2015) studied this question. NT-proBNP is associated with an increased risk of dementia and cognitive decline in the general population over a 10-year follow-up.
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