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February 6, 2026Child s Nervous SystemOpen Access

Preoperative hydrocephalus and the risk of postoperative speech impairment following posterior fossa tumour surgery in children: results from a prospective, multinational cohort study

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Authors

ALAske Foldbjerg LaustsenRFRadek FricJGJonathan Kjær Grønbæk

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Overview

Prospective cohort study investigates the impact of preoperative hydrocephalus on speech impairment in children following tumor surgery, indicating complex clinical management implications.

Key Points

  • This study aims to determine if preoperative hydrocephalus is an independent risk factor for postoperative speech impairment in children undergoing posterior fossa tumor surgery.
  • Included 800 children undergoing posterior fossa tumor surgery from 35 centers over 10 years.
  • Conducted speech and neurological assessments both before and after surgery.
  • Categorized preoperative hydrocephalus treatment as 'yes' or 'no' based on timing of alleviation.
  • Grouped outcomes of postoperative speech impairment into habitual, reduced speech, or mutism.
  • 64% of children had preoperative hydrocephalus; absence was linked to lower postoperative speech impairment risk in initial analyses.
  • After adjustment, the association between preoperative hydrocephalus and postoperative speech impairment became non-significant.
  • Treatment for preoperative hydrocephalus was associated with increased risk of speech impairment in univariate analysis but not upon adjustment.

Cite This Study

Laustsen et al. (2026) studied this question.

synapsesocial.com/papers/698585aa8f7c464f23009394https://doi.org/10.1007/s00381-026-07132-z
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preoperative Speech Impairments as Precursors of Posterior Fossa Syndrome in Children with Brain Tumours2026
  2. 2Analysis of Presurgical Language in Children with Posterior Fossa Tumours Relative to Postoperative Speech Outcomes: Findings from the European CMS Study2026
  3. 3Incidence and management of posterior fossa syndrome in children at a tertiary care hospital in Karachi: a 10-year retrospective cohort2025
  4. 4QOL-12. LESSONS LEARNED FROM LONGITUDINAL CARE IN POSTERIOR FOSSA SYNDROME2024
  5. 5ID #912 Incidence and Clinical Characteristics of Posterior Fossa Syndrome in Children with brain tumours in Western Australia2026