Key result
Radiation therapy results in no CIED malfunctions, with ~13% experiencing minor parameter changes or arrhythmias.
Why the study?
Radiation therapy can impact CIED function, prompting guidelines to recommend pre- and post-therapy device checks based on device type and dependency.
Does radiation therapy cause device malfunction or sensing issues in patients with cardiac implantable electronic devices?
Observational (n=71)
No
Does radiation therapy cause device malfunction or sensing issues in patients with cardiac implantable electronic devices?
In patients with CIEDs undergoing low-dose radiation therapy (<2Gy), no significant device malfunctions occurred, suggesting that current guideline-directed management is safe and effective.
No takes yet. Share an insight, caveat, or question.
Supports current CIED protocols during low-dose radiation; leaves open need for prospective confirmation in larger cohorts.
Witting et al. (2025) conducted an observational in Cancer patients with cardiac implantable electronic devices (n=71). Radiation therapy was evaluated on Device malfunction, detected arrhythmia, or parameter change. Radiation therapy in patients with cardiac implantable electronic devices resulted in no device malfunctions, with 12.7% experiencing non-significant parameter changes or arrhythmias.
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