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February 6, 2026MicroorganismsOpen Access

Reactive Infectious Mucocutaneous Eruption (RIME) Associated with Mycoplasma pneumoniae: Clinical and Immunological Insights from Pediatric Cases

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Authors

DMDavid M. MateaClinical Emergency Hospital BucharestRIRaluca IsacClinical Emergency Hospital BucharestEBE BoeriuClinical Emergency Hospital Bucharest

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Implication

Case series demonstrates the clinical features and importance of early recognition of RIME in children, suggesting need for prompt management.

Key Points

  • To explore the clinical and immunological aspects of reactive infectious mucocutaneous eruption (RIME) cases linked to Mycoplasma pneumoniae in a pediatric population.
  • Reviewed literature and analyzed medical records of three pediatric cases.
  • Confirmed etiologic diagnosis via Mycoplasma pneumoniae IgM serology and polymerase chain reaction.
  • Documented clinical findings including mucositis and skin involvement.
  • All patients presented with multi-site mucositis and varying degrees of skin involvement.
  • One patient required multiple hospitalizations, indicating potential for relapse.
  • All cases recovered within 10–21 days, with one experiencing skin hyperpigmentation.

Cite This Study

Matea et al. (2026) studied this question.

synapsesocial.com/papers/698585ea8f7c464f23009a49https://doi.org/10.3390/microorganisms14020364
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