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February 6, 2026European Heart Journal

A meta-analysis of the haemodynamic and echocardiographic changes following arteriovenous fistula ligation in chronic kidney disease patients

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Authors

MEM EiniehJZJ M ZaldumbideMAM Alam

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Overview

This meta-analysis examines haemodynamic and echocardiographic changes following AVF ligation in chronic kidney disease patients, suggesting improved cardiac parameters with no significant blood...

Key Points

  • The study aims to systematically review and analyze the haemodynamic and echocardiographic effects following AVF closure in patients with chronic kidney disease.
  • Conducted a systematic search of PubMed, Cochrane, and Web of Science for relevant studies.
  • Included observational studies and randomised controlled trials involving CKD patients undergoing AVF ligation.
  • Assessed key parameters indicative of cardiac and renal function.
  • Performed statistical analysis using random effects model and evaluated heterogeneity.
  • 841 patients included from 12 studies; 406 underwent AVF ligation.
  • AVF ligation resulted in a significant decrease in left ventricular mass index and left ventricular end diastolic volume.
  • Significant reduction in cardiac index observed post-ligation.
  • No significant differences found in blood pressure or left ventricular ejection fraction between groups.
  • Serum creatinine levels decreased significantly following AVF ligation.

Cite This Study

Einieh et al. (2025) studied this question.

synapsesocial.com/papers/698586118f7c464f2300a011https://doi.org/10.1093/eurheartj/ehaf784.1462
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A meta-analysis of the hemodynamic and echocardiographic changes following arteriovenous fistula ligation in chronic kidney disease patients2026
  2. 2Impact of Arteriovenous Fistula Closure on Cardiac and Renal Function in Renal Transplantation Patients2024
  3. 3Regression of Left Ventricular Hypertrophy After Arteriovenous Fistula Closure in Renal Transplant Recipients: A Long-Term Follow-Up2004 · 95 citations
  4. 4Cardiac Effects of Persistent Hemodialysis Arteriovenous Access in Recipients of Renal Allograft1999 · 70 citations
  5. 5Understanding arteriovenous fistula physiology: preoperative and early postoperative effects on left ventricular myocardial work2025