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December 1, 2004American Journal of TransplantationOpen Access

Regression of Left Ventricular Hypertrophy After Arteriovenous Fistula Closure in Renal Transplant Recipients: A Long-Term Follow-Up

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Why the study?

Does arteriovenous fistula closure reduce left ventricular mass index in kidney transplant recipients?

Population

25 kidney transplant recipients (17 undergoing AVF closure, 8 matched controls with patent AVF)

Comparison

Arteriovenous fistula (AVF) closure vs Patent AVF

Design

Cohort

Follow-up

21 months

Authors

PUPhilippe UngerSVSonia Velez‐RoaKWKarl Martin Wissing

Discussion

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Member takes

Overview

Suggests arteriovenous fistula closure may regress left ventricular hypertrophy in kidney transplant.

Structured PICO

Does arteriovenous fistula closure reduce left ventricular mass index in kidney transplant recipients?

P
Population
25 kidney transplant recipients (17 undergoing AVF closure, 8 matched controls with patent AVF)
I
Intervention
Arteriovenous fistula (AVF) closure
C
Comparator
Patent AVF (matched for age, time after AVF creation, and time after transplantation)
O
Outcome
Left ventricular mass index (LVMI) at 21 months post-closure measured by echocardiographysurrogate

Closure of large or symptomatic AVF in kidney transplant recipients induces long-term regression of LV hypertrophy, though it may increase diastolic blood pressure and concentric remodeling.

Cite This Study

Unger et al. (2004) studied this question.

synapsesocial.com/papers/6a72edbd0659c579cd60d8b6https://doi.org/10.1046/j.1600-6143.2004.00608.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac Effects of Persistent Hemodialysis Arteriovenous Access in Recipients of Renal Allograft1999 · 70 citations
  2. 2Effects of Arteriovenous Fistula on Clinical, Laboratory and Echocardiographic Findings in Renal Allograft Recipients2011 · 3 citations
  3. 3A meta-analysis of the haemodynamic and echocardiographic changes following arteriovenous fistula ligation in chronic kidney disease patients2025
  4. 4Impact of Arteriovenous Fistula Closure on Cardiac and Renal Function in Renal Transplantation Patients2024
  5. 5Understanding arteriovenous fistula physiology: preoperative and early postoperative effects on left ventricular myocardial work2025