Key result
Lower aortic pressure values reduce left ventricular shortening and external work, impairing coronary perfusion and efficiency of the heart in situ.
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Coronary perfusion pressure is a critical determinant of myocardial mechanical efficiency and must be accounted for when evaluating cardiac work in situ.
The interplay between left ventricular afterload and coronary perfusion pressure is of special significance for the heart in situ. The decrease in shortening and external work as well as the diminution in efficiency, observed at low aortic pressure values, can be attributed to impaired coronary perfusion. The coronary perfusion pressure must therefore be taken into consideration for the critical examination of the efficiency of the heart in situ.
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G. Kissling (1992) studied this question. Lower aortic pressure values reduce left ventricular shortening and external work, impairing coronary perfusion and efficiency of the heart in situ.
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