Population
19 alpha chloralose anaesthetised dogs
Comparison
Changes in coronary blood flow with or without… vs Baseline or different levels of perfusion…
Design
Preclinical
Authors
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Should not change clinical coronary perfusion management; leaves open Gregg phenomenon mechanisms for human translation.
Increased coronary blood flow enhances myocardial contractile force and systolic ventricular stiffness, which likely drives the flow-related changes in myocardial oxygen consumption (Gregg phenomenon).
Iwamoto et al. (1994) studied this question.
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