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February 8, 2026BMC Urology1 citationsOpen Access

Impact of positive surgical margin location on biochemical recurrence in pT3 prostate cancer after robot-assisted radical prostatectomy: a retrospective cohort study

MAMehmet Sefa AltayErzurum Regional Training and Research HospitalHKHüseyin KocatürkErzurum Regional Training and Research HospitalBBBanu Bedir

Key Points

  • The study aims to determine the impact of positive surgical margin characteristics on biochemical recurrence in patients with pT3 prostate cancer following robotic surgery.
  • Conducted a retrospective cohort analysis of prostate cancer patients
  • Evaluated the relationship between positive surgical margin features and biochemical recurrence
  • Examined factors such as margin length, tertiary pattern presence, and apical involvement
  • Positive surgical margin location did not determine biochemical recurrence rates.
  • Positive surgical margin length, presence of a tertiary pattern, and apical involvement were significant indicators.
  • Detailed reporting of margin characteristics improved postoperative treatment decisions.

Abstract

PSM localization alone is not a determinant of BCR; however, PSM length, the presence of a tertiary pattern, and apical involvement provide clinically meaningful prognostic information. Therefore, detailed reporting of margin characteristics in pathology reports is critically important for accurately guiding postoperative treatment strategies.

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Cite This Study

Altay et al. (2026) studied this question.

synapsesocial.com/papers/6988270a0fc35cd7a8845f08https://doi.org/10.1186/s12894-026-02069-6
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