Key result
Impella support shows 0% right heart failure and improves PVR in cardiogenic shock.
Why the study?
Does left ventricular unloading with Impella systems worsen right ventricular function in patients with cardiogenic shock?
Population
44 patients with cardiogenic shock, median age 63 years, 86% male. Excluded: patients receiving Impella for…
Design
Cohort
Follow-up
up to 72-96 hours post-implantation
Authors
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Short-term left ventricular unloading with Impella in cardiogenic shock improves right ventricular afterload without worsening RV function or coupling, suggesting right heart failure post-LVAD may be primarily surgery-related.
Cohort (n=44)
No
Does left ventricular unloading with Impella systems worsen right ventricular function in patients with cardiogenic shock?
Short-term left ventricular unloading with Impella in cardiogenic shock improves right ventricular afterload without worsening RV function or coupling, suggesting right heart failure post-LVAD may be primarily surgery-related.
D'andrea et al. (2025) conducted a cohort in Cardiogenic shock (n=44). Impella systems (Impella CP, Impella 5.0, Impella 5.5) was evaluated on Right heart failure (RHF). Impella support in patients with cardiogenic shock did not lead to right heart failure in any patient and significantly improved pulmonary vascular resistance (p=0.024).
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