Key result
Severe MAC and aortic knob calcification each linked to >50% long-term mortality post-AVR.
Why the study?
Most studies on the mortality impact of mitral annular calcification or aortic calcification following SAVR or TAVR have focused on short-term outcomes, leaving long-term survival data limited.
Does the presence of mitral annular or aortic calcification increase long-term mortality in patients undergoing surgical or transcatheter aortic valve replacement for severe aortic stenosis?
Does the presence of mitral annular or aortic calcification increase long-term mortality in patients undergoing surgical or transcatheter aortic valve replacement for severe aortic stenosis?
In patients undergoing aortic valve replacement for severe aortic stenosis, the presence of significant mitral annular or aortic calcification is associated with increased 10-year mortality.
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Significant MAC or aortic knob calcification was associated with higher post-AVR mortality; extends prior observations but leaves open prospective validation.
Kim et al. (2025) studied this question. MAC ≥180° and aortic knob calcification ≥180° were each associated with significantly higher 10-year mortality post-AVR (52.1% vs 40.7%, 64.4% vs 35.3%, respectively).
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