Key result
Multimodal assessment diagnoses 75% of ICI-associated myocarditis cases and reveals lower than reported mortality.
Why the study?
Diagnosing immune checkpoint inhibitor-associated myocarditis is crucial for timely life-saving immunosuppressive therapy, but it presents significant diagnostic complexity.
Population
32 patients referred with suspected ICImyocarditis
Comparison
Patients meeting IC-OS criteria vs not meeting criteria
Design
Retrospective case series
Authors
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May warrant multimodal assessment for suspected ICI-myocarditis; leaves open whether lower mortality reflects earlier detection or true improvement.
Diagnosis of ICI myocarditis frequently requires multimodal assessment, and contemporary cohorts may have lower cardiac mortality than previously reported due to early detection of less severe cases.
Jarabo et al. (2025) studied this question. Multimodal assessment diagnosed 75% of ICI-associated myocarditis cases; mortality was lower than reported, with overall survival 7.4±6.7 months in 24 confirmed cases.
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