The high incidence of peri-implant inflammation has become the main cause of implant treatment failure, and the improvement of the antibacterial properties of clinical oral materials is a key demand in the field of stomatology. To address this issue, we developed a coating on the surface of titanium (Ti) based on molybdenum disulfide (MoS 2 ), doped with polyphenols and copper (Cu) ions, and investigated its antibacterial properties under 808 nm near-infrared (NIR) light irradiation. The corresponding chemical composition, surface morphology, hydrophilicity, and release behavior were investigated, demonstrating the composite coating was successfully applied to the Ti. The MoS 2 /Cu composite shows a high degree of photocatalytic activity, resulting in the enhanced generation of reactive oxygen species (ROS). The addition of tannic acid (TA) enhanced the Cu ion loading capacity of the coating, and further strengthened its antibacterial properties. Moreover, the MoS 2 -based coating also demonstrates a specific photothermal effect. In vitro experiments indicate that after 10 min of 808 nm NIR, achieving antibacterial rates of 97.6% for Staphylococcus aureus (S. aureus) and 98.7% for Escherichia coli (E. coli). Therefore, this study provides a novel surface modification scheme for the early prevention of implant-related infections, which helps to reduce the risk of secondary surgeries and improve the clinical success rate of implant treatment.
Lu et al. (Fri,) studied this question.