What question did this study set out to answer?

The study aims to evaluate the effects of different antibiotic regimens on maternal and fetal outcomes in cases of preterm premature rupture of membranes after 34 weeks of gestation.

February 9, 2026MedicineOpen Access

Randomized controlled trial on the effects of different antibiotic regimens in preterm premature rupture of membranes after 34 weeks

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The study aims to evaluate the effects of different antibiotic regimens on maternal and fetal outcomes in cases of preterm premature rupture of membranes after 34 weeks of gestation.
Randomized controlled trial with 40 pregnant women diagnosed with PPROM.
Participants were divided into two groups receiving different antibiotic regimens.
Primary outcome measures included NICU length of stay and various maternal and neonatal health indicators.
Statistical analyses conducted using IBM SPSS Statistics.
No significant differences in maternal age, obstetric history, or infection markers between groups (P > .05).
NICU stay duration: Group 1 (mean 8.3 ± 6.7 days) versus Group 2 (4.3 ± 1.9 days) was not statistically significant (P = .356).
Chorioamnionitis incidence: Group 1 had 20.0%, Group 2 had 5.0% (P = .141).
Similar clinical effects in maternal and neonatal outcomes observed between the two antibiotic regimens.

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Implication

Randomized trial investigates maternal and fetal outcomes related to antibiotic regimens in PPROM.

Cite This Study

Gezen et al. (2026) studied this question.

synapsesocial.com/papers/69897996f0ec2af6756e75f0 https://doi.org/10.1097/md.0000000000047524

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Randomized controlled trial on the effects of different antibiotic regimens in preterm premature rupture of membranes after 34 weeks

Key Points

Discussion

Implication

Cite This Study

Randomized controlled trial on the effects of different antibiotic regimens in preterm premature rupture of membranes after 34 weeks

Key Points

Discussion

Implication

Cite This Study

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