Experimental study shows adverse effects of desflurane on reproductive hormones in male rats, suggesting reproductive toxicity.
Chronic inhalation of desflurane, a modern inhalational anesthetic, was found to adversely affect testicular histology, sperm morphology, and the regulation of male reproductive hormones in rats. These findings highlight potential reproductive toxicity associated with prolonged desflurane exposure.
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Dogru et al. (2026) studied this question.
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