Key result
Preeclampsia increased the risk of cardiovascular disease death by 114% compared to women without preeclampsia, with a hazard ratio of 2.14 (95% CI: 1.29 to 3.57).
Why the study?
Does preeclampsia increase the risk of subsequent cardiovascular disease death in women?
Population
Women with nonmissing parity and no previously diagnosed heart conditions drawn from a pregnancy cohort
Comparison
Preeclampsia (exposure) vs No preeclampsia
Design
Cohort
Follow-up
median 37 years
Authors
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Preeclampsia history may support closer long-term CVD monitoring in affected women; extends prior observational links but leaves causal confirmation open.
Cohort (n=14,403)
No
Does preeclampsia increase the risk of subsequent cardiovascular disease death in women?
Effect estimate: HR 2.14 (95% CI 1.29-3.57)
A history of preeclampsia, particularly early-onset before 34 weeks, is strongly associated with an increased risk of cardiovascular disease death later in life, highlighting the need for targeted screening and intervention.
Mongraw‐Chaffin et al. (2010) conducted a cohort in preeclampsia (n=14,403). preeclampsia vs. no preeclampsia was evaluated on Cardiovascular disease death (HR 2.14, 95% CI 1.29-3.57). Preeclampsia increased the risk of cardiovascular disease death by 114% compared to women without preeclampsia, with a hazard ratio of 2.14 (95% CI: 1.29 to 3.57).
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