Systematic review reveals micronuclei as biomarkers of genotoxicity in oral potentially malignant disorders, implying a need for standardized screening protocols.
Micronuclei genotoxicity is emerging as a valuable biomarker for the early detection of OPMD's. Due to its non-invasive and cost-efficient characteristics, examining micronuclei in exfoliated buccal cells could be incorporated into regular screenings for groups at high risk of OPMD and oral cancer. However, the considerable variability among studies necessitates careful interpretation and highlights the importance of establishing standardized protocols in future research.
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Chauhan et al. (2026) studied this question.
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