The HLA‐B*48:09 Allele Confirmed by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual

Key Points

• This research aims to confirm the presence of the HLA-B*48:09 allele in a specific individual using sequencing technology.
• Used Sanger dideoxy nucleotide sequencing for genetic analysis.
• Focused on the HLA-B*48 gene in a Chinese individual.
• Identified differences between HLA-B*48:09 and HLA-B*48:01:01:01 alleles.
• Confirmed HLA-B*48:09 allele presence in the individual.
• Identified a single non-synonymous nucleotide change in exon 1.