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March 24, 2026HLA

The Novel HLA‐A*02:1139 Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual

Qiu‐juan Zhu Qiang Liu Gui‐zhi Weng Pei‐pei Ding Wei‐wei Tian

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Key Points

To identify and characterize the novel HLA-A*02:1139 allele found in a Chinese individual.
Utilized Sanger dideoxy nucleotide sequencing to analyze genetic material.
Focused on identifying differences within specific alleles of HLA genes.
HLA-A*02:1139 allele differs from HLA-A*02:06:01:01 by a single nucleotide change.
This change is a non-synonymous mutation identified in exon 1.

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Implication

Identification of a new allele in a Chinese individual, suggesting genetic diversity in HLA types.

Abstract

The HLA‐A*02:1139 allele differs from HLA‐A*02:06:01:01 by a single non‐synonymous nucleotide change in exon 1.

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Cite This Study

Zhu et al. (2026) studied this question.

synapsesocial.com/papers/69c4cc85fdc3bde448917cea https://doi.org/10.1111/tan.70685

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