A new protocol synthesizes 5-arylfuran-2,3-diones from 4-aryl-2,4-dioxobutanoic acids, suggesting improved methods for chemical manufacturing.
Literature data on the main preparative methods of synthesis of 5-arylfuran-2,3-diones have been considered. A new convenient protocol has been proposed for the synthesis of these compounds by heating 4-aryl-2,4-dioxobutanoic acids with acetyl bromide in anhydrous chloroform under reflux conditions. The structure of 5-(4-methoxyphenyl)furan-2,3-dione has been confirmed by X-ray analysis.
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Derevnina et al. (2025) studied this question.
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