Synthesis of antibacterial 5-hydroxy-5-(trifluoromethyl)dihydrofuran-2,3-diones using aromatic amines, indicating antimicrobial potential.
As a result of the reaction of 5-substituted 4,4,4-trifluoroacetylfuran-2,3-diones with aromatic amines, 4-substituted 5-hydroxy-5-(trifluoromethyl)dihydrofuran-2,3-diones, were synthesized, which have antibacterial and antinociceptive activities.
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E. P. Kozlova (2025) studied this question.
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