What question did this study set out to answer?

This review aims to compare the efficacy and safety of thulium fiber laser with Holmium:YAG for lithotripsy in urinary stones.

Thulium Fiber Laser Versus Holmium:YAG for Urological Stone Lithotripsy: A Systematic Review and Meta-Analysis

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A systematic review reveals thulium fiber laser outperforms holmium:YAG in urological stone procedures, suggesting improved outcomes.

This review aims to compare the efficacy and safety of thulium fiber laser with Holmium:YAG for lithotripsy in urinary stones.
Conducted a systematic review and meta-analysis following guidelines.
Searched PubMed, Embase, Cochrane Library, and Scopus for relevant studies.
Included randomized controlled trials and cohort studies comparing TFL and Ho:YAG.
Analyzed outcomes: stone-free rate, operative time, complication rate, and retreatment rate.
Performed meta-analyses using a random-effects model and assessed heterogeneity.
Included 28 studies with 3672 patients (7 RCTs, 21 cohort studies).
TFL showed a higher stone-free rate (93.5% vs. 87.2%, p < 0.01).
Operative time was shorter for TFL (43.2 min vs. 52.8 min, p < 0.001).
Retreatment rates were lower for TFL (4.2% vs. 7.6%, p < 0.01).
Complication rates were similar between both laser types.

Samira et al. (2026) studied this question.

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