Prevention of bisphosphonate related osteonecroses of the jaw using autologous platelet concentrate

Introduction: Platelet-rich fibrin (PRF) is now widely used in various fields of medicine, including tissue regeneration. The aim of the work was to analyze the effect of PRF on improving postoperative wound healing in a patient with a risk of developing bisphosphonate osteonecrosis of the jaws. Case report: A 71-year-old woman, who is on bisphosphonate therapy due to generalized osteoporosis, came to the clinic with an indication for surgical extraction of an impacted upper left canine. Oral surgical treatment was performed after a three-month interruption of therapy. During the surgical extraction of impacted teeth, a platelet-rich fibrin is placed and covered with a platelet-rich membrane. The wound healing was successful. Conclusion: The use of PRF for oral surgical interventions in patients taking BPs appears to be a promising solution and an excellent alternative treatment for the healing of oral tissues.