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April 1, 2026Clinical and Experimental Dental ResearchOpen Access

Advanced Platelet‐Rich Fibrin in Surgical Management of Medication‐Related Osteonecrosis of the Jaw: A Prospective Case Series Study

Besim Hajdari L Morina Granit Gashi Gloriosa Dobra Besir Salihu Venera Bimbashi

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Key Points

This research aims to evaluate the effectiveness of A-PRF in enhancing surgical outcomes for MRONJ patients.
Conducted a prospective case series on patients undergoing MRONJ surgery
Administered adjunctive A-PRF during surgical procedures
Monitored soft tissue healing and overall clinical improvement
A-PRF use resulted in favorable soft tissue healing
Patients showed clinical improvement post-surgery
Findings suggest a positive role for A-PRF in surgical management

Implication

Prospective case series demonstrates improvement in soft tissue healing during MRONJ surgery, implying potential benefits of A-PRF.

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Cite This Study

Hajdari et al. (2026) studied this question.

synapsesocial.com/papers/69e471ef010ef96374d8e2cb https://doi.org/10.1002/cre2.70346

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Platelet-Rich Fibrin in Surgical Wound Healing of Medication-Related Osteonecrosis of the Jaw: A Pilot Clinical StudyCohort Study · 2026 · 1 citations
2Adjuvant A-PRF Application in Patients with Various Stages of Medication-Related Osteonecrosis of the Jaw (MRONJ): Case Series2025
3Autologous Platelet Concentrates in the Management of Medication-Related Osteonecrosis of the Jaw: A Systematic Review2025 · 5 citations
4Platelet-Rich Fibrin Treatment Evaluation in Patients with Medication-Related Osteonecrosis of the Jaw and Osteoradionecrosis2024 · 2 citations
5Application of Platelet-rich Fibrin as a Method of Treatment for Medication-related Osteonecrosis of the Jaws in Bulgaria2024