Advanced Platelet‐Rich Fibrin in Surgical Management of Medication‐Related Osteonecrosis of the Jaw: A Prospective Case Series Study | Synapse
April 19, 2026Open Access
Advanced Platelet‐Rich Fibrin in Surgical Management of Medication‐Related Osteonecrosis of the Jaw: A Prospective Case Series Study
Key Points
This research aims to evaluate the effectiveness of A-PRF in enhancing surgical outcomes for MRONJ patients.
Conducted a prospective case series on patients undergoing MRONJ surgery
Administered adjunctive A-PRF during surgical procedures
Monitored soft tissue healing and overall clinical improvement
A-PRF use resulted in favorable soft tissue healing
Patients showed clinical improvement post-surgery
Findings suggest a positive role for A-PRF in surgical management
Abstract
Adjunctive use of A-PRF in MRONJ surgery was associated with favorable soft tissue healing and clinical improvement. Larger controlled studies are needed to confirm these findings.