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February 12, 2026Journal of Biomaterials Science Polymer Edition

3D-printing technologies and biomaterial innovations for bone tissue engineering: current status and future perspectives

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Authors

SHShimaa HusienAmerican University in CairoIAIsra H. AliWinnMedWMWael MamdouhAmerican University in Cairo

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Implication

This review discusses innovative 3D printing techniques enhancing bone regeneration in clinical applications, suggesting improved outcomes.

Key Points

  • The aim is to assess the current state and future potential of 3D printing and biomaterials in bone tissue engineering.
  • Overview of bone anatomy, fracture types, and healing mechanisms.
  • Discussion of clinical strategies for bone regeneration, including casting and grafting.
  • Examination of key 3D printing techniques like stereolithography and bioplotter printing.
  • Assessment of different biomaterial classes used in scaffolds.
  • Exploration of challenges in vascularization and regulatory considerations.
  • 3D-printed scaffolds show promise for improved bone healing and regeneration.
  • Integration of nanotechnology enhances scaffold biofunctionality.
  • Emerging trends in 4D implanting highlight the dynamic nature of future scaffolds.
  • Identification of ongoing challenges such as mechanical optimization and immune compatibility.

Cite This Study

Husien et al. (2026) studied this question.

synapsesocial.com/papers/698d6e2a5be6419ac0d539fchttps://doi.org/10.1080/09205063.2026.2625836
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Advances in 3D-printed and biofabricated scaffolds for bone tissue engineering: materials, fabrication and biological integration2026
  2. 2Advances in 3D-Printed scaffolds for bone defect repair: material strategies and synergistic functional performance2025
  3. 3Innovative designs of 3D scaffolds for bone tissue regeneration: Understanding principles and addressing challenges2024 · 82 citations
  4. 43D Bio printed Biomimetic Bone Scaffolds for Osteoporotic Fracture Repair2025
  5. 5Bone Tissue Engineering: Scaffold Design Principles, Biomaterial Advances, and Strategies for Functional Regeneration and Clinical Translation2026 · 7 citations