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November 12, 2025Frontiers in Bioengineering and BiotechnologyOpen Access

Advances in 3D-Printed scaffolds for bone defect repair: material strategies and synergistic functional performance

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Authors

XTXijie TangHXHaijia XuXLXiang-Zhong Liu

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Overview

Review highlights advances in 3D-printed biomaterial scaffolds, improving osteogenesis and vascularization for bone repair.

Key Points

  • Bioactive 3D-printed scaffolds improve osteogenesis and vascularization in bone defects, with polymers and ceramics utilized for enhanced performance.
  • Recent developments focus on mechanics, degradation, and biological function in scaffolds, integrating surface modifications for superior outcomes.
  • Review analyzes various materials and strategies, including grafts and composites, to optimize scaffold design in clinical applications.
  • Future research aims to standardize clinical applications and innovate materials to enhance the effectiveness of bone regeneration strategies.

Cite This Study

Tang et al. (2025) studied this question.

synapsesocial.com/papers/69252e83c0ce034ddc3559f6https://doi.org/10.3389/fbioe.2025.1707406
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